DIFFERENCES BETWEEN THE EUROPEAN UNION AND UNITED STATES OF AMERICA IN DRUG REGULATORY AFFAIRS AFFECT GLOBAL PATIENT SAFETY STANDARDS AND PUBLIC HEALTH AWARENESS: THE CASE OF DEFERASIROX AND OTHER IRON CHELATING DRUGS

Regulatory policies on drugs have a major impact on patient safety and survival.Some pharmaceutical companies employ all possible methods to achieve maximum sales in relation to the monopoly of their patented drugs, leading sometimes to irregularities and illegal activities.Misinformation on the orphan drug deferasirox has reached the stage of crim

Abstract The uncertain identity of Hyla x-signata Spix, 1824 has been a pervasive problem in the taxonomy of the genus Scinax.A species supposedly distributed from northeastern Brazil northwards Lanyard to Colombia and Venezuela, described in a few lines without much information and with an accompanying figure, and its type specimen lost during Wor

The new coronavirus, SARS-CoV-2, first identified in humans in Wuhan Province, China, in December 2019, has spread rapidly throughout the world, causing World Health Organization (WHO) to declare it a pandemic infection.This pathogenic agent belongs to the genus beta-coronavirus, alongside SARS (Severe Acute Respiratory Syndrome) and MERS (Middle E

In the process of robust controller design for aircraft engines, it is difficult to divide the flight envelope re-gion systematically.In this paper, the flight envelope division methods for aircraft engines based on thrust fuel con-sumption rate characteristics and dynamic pressure fuel consumption rate characteristics is proposed.According to the

A promising open inguinal hernia operation called Onstep was developed in 2005.The technique is without sutures to the surrounding tissue, causing minimal tension.A specific mesh is used with a memory recoil ring in the border, which may cause pain superficial to the lateral part of the mesh for slender patients.The Sleeping Aid aim of this study w